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Raltitrexed adalah obat anti-tumor untuk kanker kolorektal lanjut.enzim kunci dalam konversi biokimia dari dUMP ke dTMP. It enters the cell via the reduced folatefmethotrexate cell membrane carrier and is converted to the polyglutamate species by folylpolyglutamate synthase within 4h where it then binds to the folate substrate site of TS.
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Raltitrexed (112887-68-0) |
CAS:112887-68-0; CAS:112887-68-0; anti-tumor ; anti tumor; thymidylat
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6-Bromomethyl-3,4-dihydro-2-methyl-quinazolin-4-one (112888-43-4) |
CAS: 112888-43-4; anti-tumor; timidylate synthase; spesies poliglutamat
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5-[N-(tert-butoxycarbonyl) -N-methylamino]-2-thiophenecarboxylic acid (131052-68-1) |
CAS: 131052-68-1; CAS: 131052-68-1; anti-tumor ; anti tumor; thymidyl
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5-Nitrothiophene-2-carboxylicacid (6317-37-9) |
CAS: 6317-37-9; anti-tumor; timidylate synthase; spesies poliglutamat
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